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Compound in Abortion Pill May Prevent Breast and Ovarian Cancer

December 26th, 2008 by admin | No Comments | Filed in Uncategorized

The chemical compound in the “abortion pill” has been found to prevent the development of mammary tumors caused by the mutant gene responsible for the majority of breast and ovarian cancers, a group of scientists from UC Irvine reported.

The key compound, known as mifepristone, prevented breast tumors by inhibiting the production of progesterone. progesterone is a hormone involved in the female reproductive cycle which is found in the tissues of the breast. The discovery may open up more, and far more palatable options for women who have a genetic predisposition to developing breast and ovarian cancers. Currently, the typical prevention method relies on the surgical removal of breasts or ovaries for the majority of these women.
The study is published in the December 1 issue of Science.

“We found that progesterone plays a role in the development of by encouraging the proliferation of mammary cells that carry a gene,” said Eva Lee, the study’s lead author and a professor of developmental and cell biology and biological chemistry at UCI. “Mifepristone can block that response. We’re excited about this discovery and hope it leads to new options for women with a high risk for developing .”

In the study, Lee and her colleagues addressed how mifepristone affects the functionality of mutated genes called BRCA-1 genes. This group of mutated genes is widely studied by cancer researchers because a mutated version of this gene significantly contributes to the development of breast and ovarian cancers. By the age of 70, more than 50 percent of women with the mutated BRCA-1 gene develop these cancers.

The researchers studied mice that possessed the mutated BRCA-1 gene. Mice treated with mifepristone, an anti-progesterone compound, did not develop mammary tumors after 12 months. All of the untreated mice developed tumors by eight months of age.

Progesterone, secreted by the ovaries, is essential to the term of a pregnancy. Mifepristone, also called RU486, is designed to abort pregnancy in the first trimester by shutting down the secretion of progesterone and ending the viability of the fetus. In smaller doses, it is also an emergency contraceptive.

UCI researchers found that progesterone encourages the development of cancer when the mutated BRCA-1 is exists because it increases the rate of cell division. Mifepristone, they discovered, blocked a binding process that is necessary for progesterone to cause the cells to divide.

Previous studies have linked high levels of progesterone with an increased risk of . This was proven to be especially true for menopausal women who received hormone-replacement therapy that included progesterone and estrogen to ease things like hot flashes and night sweats. The previous findings, combined with this new data, lead scientists to believe that anti-progesterone could provide women at risk with more prevention options in the future.

The research was conducted with the backing of the National Cancer Institute, the Breast Cancer Research Foundation and the Department of Defense.

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How To Have Great Prostate Health

December 26th, 2008 by admin | No Comments | Filed in Uncategorized

When you are young, you should have great prostate health. Even after the age of 50 you should also not be suffering from cancerous conditions because your body is designed to stop most cases of cancer before they even start i.e. mutated cells are killed by the immune system before even the smallest of tumours can form.

The above holds particularly true if you eat healthily and have healthy habits. Unfortunately it is hardly the case nowadays. Continued prostate health is not possible if you do not make certain necessary changes.

Firstly, your weight. It is important that you try to maintain your overall health and a sensible weight because obesity is one of the leading risk factors associated with bad prostate health and in particular . Obesity is often caused by a bad diet i.e. one containing large amounts of saturated fat and dairy products, in combination with a general lack of exercise.

Exercise strengthens the body and makes it harder for infections to take hold. Exercise does not have to involve an expensive gym; you can go for a jog or join in with an exercise video. Anything that increases your heart rate and burns excess fat will ultimately help to ensure continued prostate health.

Consuming a diet that comprises of plenty of fruit and fresh vegetables will help to keep the body’s immune system at its peak. Many of the produce contain antioxidants which are thought to get eliminate potentially harmful free radicals from the body.

You should also stop smoking. Your prostate health is likely to be affected if you smoking cigarettes or any nicotine containing product. Nicotine is a known carcinogenic i.e. cancer-causing chemical, and ingesting it on a daily basis can have severe effects on both your immune system and many of the systems that make up your body. While nicotine affects the respiratory system more than the rest of the body, prostate health can also suffer as a result of smoking.

You should also make an effort to learn the signs and symptoms commonly associated with bad prostate health such as urinary problems and penile dysfunction. By knowing what symptoms to look out for, you can be aware of any potential problems at their early stages. Getting yourself treated will be a much easier process.

Maintaining good prostate health is entirely up to you. Making a few small changes to your lifestyle can greatly reduce the chances of you developing a potentially lethal prostate condition. You should always go for regular medical check-ups, especially if you are over 50 years of age. Do not be embarrassed about seeking for medical help if you should experience symptoms of poor prostate health.

Early detection helps in your recovery and your prostate-cancer-treatment-hub.com/Articles/Prostate_Cancer_Treatment.php treatment. For more information, please visit the site at Prostate-Cancer-Treatment-Hub.com Prostate-Cancer-Treatment-Hub.com

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Life After Cancer

December 26th, 2008 by admin | No Comments | Filed in Uncategorized

I may have run 6 marathons, the last one 7 months after surgery and for , but I am no Lance Armstrong. Lance, as many of you know, was diagnosed ten years ago with testicular cancer that had spread to his lungs and brain. He survived surgery and gruelling to come back and win the Tour de France, arguably the world’s toughest cycle race. He won it not once, but 7 times in a row. Now that guy is a legend.

As for me, I am a back of the pack runner: slow and steady. I was never going to be running up the front with a double D cup chest size. I think even Lance would struggle should he have been so endowed.

I run not to win the race, but to celebrate life, living, and being alive. This is ironic really because after running for 5 hours you really do feel half-dead!

Seriously though, it is a real privilege to be here. There are so many other people who could have stood up and told their stories.

If you’re like me, you feel that cancer is everywhere. Every day it seems someone new is diagnosed with some brand of cancer. And it’s not a nice disease.

My good friend’s brother in law has recently had a tumour removed from his neck. The surgery affected function in his left arm and the radiotherapy killed his saliva production. He finds it difficult to swallow and can’t taste anything ever again. No more red wine, no more chocolate, no more Krispy Kremes. I guess the up side is that if you can’t taste it, you won’t have cravings for red wine, chocolate and Krispy Kremes.

As for me, I was diagnosed with four days after my gorgeous husband Rob proposed. There I was – 35, first proposal, never been married, excited to get married, to start a family. Then the doctor says, “You have . You may need a hysterectomy.”

I felt like I stepped in to the middle of a silent hurricane. There was a roar and a rage that spun my life in a direction I had never anticipated.

I had surgery – an operation called a radical trachelectomy – removal of the cervix. It is a very new procedure, reserved for young women who want to preserve their fertility and whose cancer has not spread. In theory I can still fall pregnant, though not without some careful management.

After surgery I lay on my hospital bed with tubes sticking out everywhere. The surgeon came in, sat down on the bed, and patted my knee. You know it’s bad when a surgeon, usually clinical and dry to a fault, sits down and pats your knee. He told me they found cancer in one of the lymph nodes they removed. I was going to need four rounds of .

Chemotherapy, for those who have not experienced it, is no picnic. There are all sorts of chemicals they use to poison the cancer cells. My particular form of consisted of a 9am to 5pm experience. I had an hour of fluid dripped through my arm, and then a couple of hours of cysplatin –the drug – then another hour of fluid to help flush it through. Cysplatin, like many other drugs, is so toxic that the nurses put on protective eyewear, enormous rubber gloves, and a mask just to hook it up. And then this drips directly in to the vein.

People often ask me, “What was it like? What did the chemo experience feel like?” I tell them, imagine your worst hangover ever, and nothing you do makes it feel any better. Not drinking, not sleeping, not eating. And this lasts for ten days.

No doubt about it – cancer sucks.

In my mind, the worst bits of cancer are:
1. Being told you have it
2. Waiting for test results
3. The treatment itself
4. After treatment.

Once treatment was over, it was the strangest thing. As I walked through those electric sliding glass doors after my last round of chemo, I felt like I was wandering out in to a giant wilderness. What now? What next?

You don’t ever really get an “all clear” after cancer. It is not like appendicitis where you have it out and it is all done. Instead you live and wait between checkups to see if the cancer has returned or not. Each check up is one step further away from the chance of recurrence. But there are no guarantees.

How do you live like this? How do people cope?

Really, you just go on. You live each moment as it happens.

However there are gifts in cancer too, strange as it may seem… Lance Armstrong says he would never regret having cancer for the gifts it gave him, how it helped him to grow as a person. I, too, discovered some unexpected gifts in my cancer journey.

These are the gifts I discovered through my cancer journey:

1. I have never felt so loved. I had so much support from my friends, colleagues, and family. People gave me books, CDs, movies, flowers, brought me soup, chocolate, and plenty of other goodies. I experienced a real tsunami of love. People around the world were praying for me, some I had never met. I felt connected and cherished.

However the gift was not that cancer caused love to flow; rather it was the realisation that this love had been around me all the time but I had been so busy, so focused on my narrow little life, that I did not feel open to it. Like a sledgehammer, cancer cracked open my awareness to giving and receiving an abundance of love. I feel it flow effortlessly in my life now.

2. Compassion. I gained a lot more compassion for people – you just never know what they have been through. My own doctor, the one who diagnosed my cancer, told me that she too had gone through the cancer merry-go-round. She was diagnosed 7 years ago with . 3 weeks later her husband was diagnosed with liver cancer. He promptly died, leaving her with four kids to look after while undergoing .

I felt such a deep compassion for this woman who had hitherto just been a busy G.P. to me. I now treat every encounter with another person with a lot more grace and care. I approach them from a foundation of compassion. This is a much more gentle and peaceful way to engage with others.

Most important of all, I gained compassion for myself. I stopped judging myself so harshly, stopped trying to be perfect. I came to enjoy all the lumps, and bumps, and bits and boobs that before had caused me so much grief. I loved my body, my imperfections, because it was alive – I was alive.

3. In facing death, I learned about life. After round two of I lay on my bed, feeling dreadful, gazing out the window at the trees. I just wanted to hide under the doona, terrified of dying. I just wanted to hug my mummy and daddy.

Instead I started to notice the sunlight on the leaves, the blue of the sky, the rosellas on the grass. It was magic. And I realised that everywhere there was a compulsive and unrelenting push for life.

Miracles were everywhere: the birds looking for a meal, the kangaroos nibbling on grass, spiders in their webs, the miracle of a baby in the womb growing without any help at all – these miracles were happening without any conscious thought from any of us. I realised I was part of that. This unrelenting push for life was part of me too. We are all part of that.

I felt this realisation fill all the cells of my being. I felt peace descend upon me. I was part of this; I am part of this; we are all part of this life. No matter what happens to our bodies or to things around us, it will be ok because we are all part of this enormous surging river of life that is so beautiful and so amazing and so full of miracles.

And that was what cancer gave me – an awareness of the true nature of life itself.

I know there are some of you here tonight who are living with a cancer diagnosis and undergoing treatment. I know you are terrified. I was too. But whether you have cancer or not, none of us knows what is going to happen tomorrow, next week, or in five years from now. You can choose to live in fear, or you can choose to live in possibility and joy.

All any of us ever have is now, this moment – right here right now. And those moments are magic.

If you take a message away with you tonight, it’s not that there is life after cancer, but that there is life. Make sure you live it.

Copyright 2006 Zoë Routh, Inner Compass, innercompass.com.au www.innercompass.com.au

Cancer survivor Zoe Routh is the Head Coach at Inner Compass, a personal development organisation that helps busy professionals work less and achieve more. Inner Compass offers practical strategies and solutions to improve personal effectiveness and live an inspired life.

Zoe has worked with groups and individuals since 1987. She has worked as a trainer, coach and facilitator in helping people achieve their personal best.

Inner Compass offers articles, resources, and coaching programs to help busy professionals radically improve their personal effectiveness to live an inspired life.

innercompass.com.au innercompass.com.au

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Lung Cancer: Basic Facts

December 26th, 2008 by admin | No Comments | Filed in Uncategorized

We all have heard of but how many of us are well aware of its symptoms? The is one of the most perilous diseases that kill thousands of Americans every year and each year the number of cases are increasing. With the occurrences of on the rise, it is essential that we learn about the basic factors leading to and what should be the courses of action in case of diagnosis. Here are the basic information regarding that will help you to understand how and when it develops and how to steer clear of this killer disease.

Lung cancer is that condition of your lungs where an abnormal reproduction of cells takes place. And it can happen in one or both of your lungs. Sometimes lumps of cancerous cells or the tumors invade the organs. Our lungs allow the oxygen from the air to pass into the bloodstream and carbon dioxide to eliminate from the system. Now any kind of lung disease including impairs this function of lungs to transfer oxygen into blood and remove carbon dioxide from it. The result is many kinds of disorders relating to breathing trouble and cough.

Do you know what the most dreadful part of the is? One rarely comes to suspect that he or she is suffering from until it is too late and goes beyond any kind of treatment. This is because, signs and symptoms associated with are never acute or alarming until the later stages of malignancy and it is often at this stage when someone starts to experience the typical symptoms of . So it is recommended that if you ever experience any symptom even remotely related to , rush to the doctor without delay so that in case of diagnosis of you can avail the treatments as early as possible. The earlier the disease is diagnosed; greater are the chances of survival.

So what are the common symptoms of ? Nagging cough that seems never to end coupled with constant chest pain may be the warning of something being grossly wrong with your lungs. If you are suffering from recurring pneumonia or bronchitis, it may be an indication that you should immediately see an oncologist. The person displaying certain apathy for food followed by a remarkable weight loss may be an indication of and the patients of often complain of fatigue. However, swelling of neck and face is also one of the symptoms of .

Remember can be prevented if you give up smoking. So stay away from the cigars, cigarettes, pipes and other tobacco products. Also insist that the smokers should always smoke inside the smoking zone; do not allow the second hand smokes damage your lungs.

Barney Garcia writes about lung disease and topics. Visit: help-lung-cancer.info/sitemap.php Lung Cancer Articles and help-lung-disease.info/sitemap.html Lung Disease Articles

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