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Treatment Options for Mantle Cell Lymphoma

June 22nd, 2008 by admin | Filed under Uncategorized.

A rare form of the Non-Hodgkin disease is the Mantle cell . This disease is quite dangerous because its tumor grows very fast and ends up affecting most of the organs.
Generally, people are diagnosed with mantle cell only when the disease has affected more organs and so, treating them is a little bit difficult because several areas of the body must be treated in the same time. The most indicated treatment in this case is .

Chemotherapy tries to stop cancerous cells from growing or dividing. There can be used oral drugs or drugs injected into the vein or muscle that will reach the cancer cells by entering the bloodstream, and is called systemic . In mantle cell doctors use a combination of four drugs administered in a single day and then repeated every 3 weeks for 6 times.

In most of the cases, mantle cell therapy is not useful and even if the response to the treatment seemed to be good, the disease comes back very often. In preventing this, doctors have used different drug combinations and the most successful was one treatment used in too. This treatment is unbearable for many of the patients due to its side effects, and doctors will not recommend this drug combination if they feel that the patient will not tolerate the treatment.

In most cases, after is done, stem cells previously taken from the patient’s blood or bone marrow or from a donor will be thawed and replaced through an infusion, in order to restore the body’s blood cells destroyed by the .

Biological therapy has proved to be useful in treating many forms of , and it uses monoclonal antibodies. These antibodies are made from an immune system cell and are designed to seek and destroy all the substances that can help cancer cells to grow and develop. One of the monoclonal antibodies used in treating Non-Hodgkin is Rituximab. This antibody could be used in treating mantle cell too.

There have been developed some new drugs but they are still under tests in clinical trials. Bortezomib is one of them and using it seems to lead to the death of cancer cells.

Using radiation therapy proved to be inefficient because it did not lead to a remarkably extinction of the cancer cells and it only weakened the human organism.

Until now there is no cure for this disease and no certain effective treatment. In order to discover a useful therapy, doctors will encourage you to join a clinical trial and help them improve the medical treatment of this terrible disease.

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